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If a threshold is reached that has been defined in the study protocol, the process stops

J Leukoc Biol 104:499514 Gallegos-Alcal P, Jimnez M, Cervantes-Garca D, Salinas E (2021) The keratinocyte as a crucial cell in the predisposition, onset, progression, therapy and study of the atopic dermatitis

MeHg not only induces GSH depletion 39 but also binds to the thiol groups of at least two thioredoxin forms (Trx1 and TrxR) inhibiting their function, a proposed major molecular mechanism of mercury toxicity 38

Amazingly, researchers actually applied topical glutathione to brain injuries in mice and found that glutathione was able to prevent cell death